Correlation between Human Epidermal Growth Factor Receptor and Hormonal Receptor Status with Grade and Nodal Status in Carcinoma Breast: A Prospective Observational Study
Manjunath Ka, Rohit Krishnappaa, Raksha Ravikumarb, S. Rajagopalanc
aAssistant Professor bJunior Resident cProfessor and Head, Department of General Surgery, Rajarajeswari Medical College and Hospital, Kambipura, Mysore Road, Bangalore, Karnataka 560074, India.
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Breast carcinoma is the most common malignant tumor and the leading cause of carcinoma death in women. Tissue evaluation gives information about various receptors which are yield prognostic information for further treatment. Identification of clinically predictive and prognostic factors is considered as an important issue in treatment of breast cancer. There are a number of tumor related features available to predict the prognosis of breast cancer. The involvement of axillary lymph nodes (ALNs) is the most important prognostic factor in operable primary breast cancer. In our study we try to find out the correlation between human epidermal growth factor Receptor (HER-2/neu) and hormonal receptor status (Estrogen/Progesterone ER,PR) with grade and nodal status in carcinoma breast.
Corresponding Author : Rohit Krishnappa, Assistant Professor, Department of General Surgery, Rajarajeswari Medical College and Hospital, Kambipura, Mysore Road, Bangalore, Karnataka, India 560074.