Despite improvements in prevention, Surgical site infections remain a significant clinical problem as they are associated with substantial mortality and morbidity and impose severe demands on healthcare resources. With the objective of evaluating the surgical site infections in different classes of wounds in Safdarjung Hospital and compare them with the expected international standards, to understand the risk factors associated with them and to study the microbiological profile, a study was conducted during the period (10 June 2010 to 8 August 2010).