Open Access: View PDF

DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.9217.7

Abstract

The aim of the study was to perform Carotid Doppler in children aged 215 years with Sickle cell anemia. We also studied transcranial velocities in Internal carotid arteries & mean velocities in Common carotid, External carotid and Vertebral arteries. Correlation of increased velocity of blood flow with number of blood transfusions in past, HbF levels and Hydroxyurea therapy was also studied. Materials and Method: It was a hospital based crosssectional study conducted in a Tertiary care hospital in Nagpur from 1st March 2016 to 28 February 2017. Results: Total 64 patients were enrolled. 51.6% ofpatients were in age group of 510 years. Transcranialvelocity in Internal carotid artery between 170200cm/ s was present in 37.5% of patients and 6.25% of patients had TCV of >200cm/s. There was no correlation of TCV with number of blood transfusions in past andHbF levels. Patients who were on Hydroxyurea therapy had reduced transcranial velocities as compared to those who were not on therapy.

Keywords: Transcranialvelocity; Sickle Cell Anemia; Hydroxyurea. 

Corresponding Author : Kiran Gaikwad, Assistant Lecturer, Dept of Pediatrics, NKP Salve Institute of Medical Science & Lata Mangeshkar Hospital, (NKPSIMS & LMH), Nagpur, Maharashtra 440019, India.