Ependymomas commonly arise from conus medullaris, cauda equina and filum terminale. Ependymoma involving single nerve root is rare. We report a case of young male with disabling low back pain without motor- sensory deficits whose magnetic resonance imaging (MRI) showed a intradural lesion opposite L2- 3 vertebral body which was confined only to the S1 nerve root and was resected without incurring any post operative deficits. Pathologic examination was suggestive of myxopapillary ependymoma. Patient was asymptomatic postoperatively and MRI did not show residual disease. Ependymomas can cause central nervous system dissemination (CNS), recur and undergo malignant transformation, knowledge of which is essential for management and follow up. We believe this is the first reported case of S1 nerve root Ependymoma.

Keywords: Ependymoma; Nerve Root; Sacral.