Introduction: Platelet plays an important role in atherosclerosis, the major cause of unstable coronary syndromes. Despite an increasing volume of literature which suggests that platelet volume measurement might be useful in the diagnosis of disorders of thrombopoisis, platelet parameters have not been utilised by the clinicians. The clinical utility of newer haematological parameters such as platelet indices has been explored in recent years. Mean platelet volume (MPV) is an indicator of platelet activation and it has been reported to increase in acute myocardial infarction and acute coronary syndromes Material & methods: The present study is to determine the relationship between mean platelet volume and platelet count, and also to assess the normal range for mean platelet volume in 500 healthy adults in Indian population. Result: The range of platelet count in the normal subjects was 26 – 490*103/ul with a mean of 194*103/ul . The range for platelet volume was 6 – 10.9fl with a mean of 7.4fl. . It was found that the platelet count and mean platelet volume were found to be inversely proportional to each other. Conclusion: Hence from our study we found the mean volume to be 7fl and mean platelet count was 194*103/ul. The count and volume showed an inverse relationship. Patients having a low platelet count had a higher MPV and patients with high platelet count had a low MPV. The patients having a MPV beyond 11.7 fl should be evaluated carefully especially for occlusive arterial diseases.

Keywords: Mean Platelet Volume; Platelet Count; Healthy Population.