Introduction: Surgical removal of testis is indicated in testicular tumors, male breast carcinoma, and prostate cancer as well as in many non-neoplastic lesions like-undescended testis, torsion, epididymo-orchitis, hematocele and testicular atrophy. Testicular atrophy secondary to testicular injury and infections are common next to cryptorchidism. Testicular tumors comprise only 1% of all cancers in men. Aims and Objectives: Study of histomorphological spectrum of lesions in orchidectomy specimens and to determine the frequency of various testicular tumors. Materials and Methods: This is a retrospective study of orchidectomy specimens received from January 2009 toJanuary 2013. The specimens were grossly examined, fixed in 10% neutral buffered formalin. All H & E sections were reviewed. Results: Out of the 63 orchidectomy specimens received, 46 (73.01%) were non-neoplastic while 17 (26.98%) were neoplastic lesions. Among the non-neoplastic lesions, chronic epididymo orchitis was the commonest, followed by atrophic testis, organized hydrocele, acute epididymo-orchitis, pyocele and others. Whereas, neoplastic lesions ranged from seminoma being the commonest followed by mixed germ cell tumors, lymphoma, pure germ cell tumors, spermatocytic seminoma and metastatic prostatic adenocarcinoma. Conclusion: Testicular pathology is a nosologically complex subjectbecause of the spectrum of histologic subtypes and variableclinical behaviour. Currently, treatment for most of the testicular neoplasms is orchiectomy, surveillance and radiation to the affected testis. Hence present study was undertaken to study thehistomorphological spectrumof lesions in orchidectomy specimens.

Keywords: Epididymo-Orchitis; Metastatic; Orchidectomy; Seminoma; Testicular Tumours.