Context: Blood transfusion is a life saving measure in various medical and surgical emergencies. Transfusion medicine, apart from being important for the medical treatment of each patient, also has great public health importance. Aims: The aim of our study was to know the prevalence of transfusion transmissible infections among blood donors in our college hospital blood bank. Settings & Design: Retrospective study conducted for 2 years. Methods & Material: This was a retrospective study conducted at the blood transfusion centre of a tertiary care hospital.Voluntary donors were evaluated for the prevalence of HIV, HBS Ag, HCV, Syphilis and Malaria. All the samples were screened by third generation ELISA Kits for HIV, HBsAg and HCV, by Rapid Plasma Reagin method for Syphilis, and by Immunochromatographic test for detection of Plasmodium falciparum and Plasmodium vivax antigen. Results: Total number of voluntary blood donors in the two year period were 3355. The seroprevalence of HIV, HBsAg, HCV were 0.42%, 1.88% and 0.29% respectively. No blood donors were tested positive for syphilis and malaria. Conclusions: Blood is still one of the main sources of transmission of infections. HIV, HBsAg , HCV are still prevalent among voluntary donors.

Keywords: Seroprevalence; Hepatitis B.; Hepatitis C.; Human Immunodeficiency Virus; Donors.