AbstractIntroduction: Hysterectomy is the most common major gynaecological surgery done in the world. Common reasons include abnormal uterine bleeding (AUB) and leiomyoma. Aim and Objectives: This study was done to assess the indications and associated pathological findings among hysterectomy cases in our centre. Materials and Methods: This was a prospective study conducted over a period of three years from Jan 2014 to Dec 2016. All cases of hysterectomy conducted for gynaecological reasons were included in the study. Results: A total of 319 cases were included in the study. Most of the patients who underwent surgery were in the 4th and 5th decade. Common clinical indications included AUB and fibroid. In 45.76% of the hysterectomy specimens, no significant pathology was identified. Most significant histopathological findings were leiomyoma followed by adenomyosis. Conclusion: Hysterectomy still continues to be the surgery of choice for benign conditions, even though in developed countries, it continues to reduce with advent of newer methods. Larger studies are necessary to identify the reasons for hysterectomy, and to avoid hysterectomy for benign conditions, particularly in our part of the world.