AbstractOral Submucous Fibrosis (OSMF) is a chronic debilitating disease of the oral cavity characterized by inflammation and progressive fibrosis of the submucosal tissues. It results in marked rigidity and an eventual inability to open the mouth. The buccal mucosa is the most commonly involved site, but any part of the oral cavity can be involved, even the pharynx. It is characterized by oral pain and burning sensation upon consumption of spicy foodstuffs, increased salivation, change of gustatory sensation, dryness of the mouth and trismus. It also represents with impaired mouth movements, Dysphagia to solids, Hearing loss due to stenosis of the eustachian tubes and Nasal tonality to the voice, etc. Number of medical and surgical therapies is still in progress to obtain the best therapeutic remedy for its effect management. But, still no drug is approved for the better management of this condition. On the contrary part the incidence of this condition is rising due to faulty food habits and addictions since childhood. Along with the routine management application of topical anesthetic agents to control the local symptoms is a common practice, which alter the taste perception and alter digestion of food significantly. Matsyaakshi (Alternanthera sessilis) is a traditional drug of choice for controlling the pain in oral cavity. This controls the pain in oral cavity rather than altering the taste perception and thus, does not interfere with the digestion
Keywords: Oral Submucosal Fibrosis; Matsyakshi; Dysphagia; Trismus; Eustachian; Anaesthesia.